SynopsisTV Series (1998-2000). 2 Seasons. 42 Episodes. Jesse was a sitcom which ran on NBC from 1998 to 2000. The show was created by Ira Ungerleider, formerly a writer on Friends. The show starred Christina Applegate, formerly of "Married... with Children" fame, as a single mother named Jesse Warner, raising her nine-year-old son in the big city. She worked for her father in a German-themed bar in Buffalo, New York, serving beer while wearing ...